Small ubiquitin-related modifier 2

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August undefined, 2024

WebSmall ubiquitin-related modifier 2 is a protein that in humans is encoded by the SUMO2 gene. [5] Function [ edit] This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. WebSmall ubiquitin-related modifier 2/3 interacts with p65 and stabilizes it in the cytoplasm in HBV-associated hepatocellular carcinoma. Data show that substantial increases in the …

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WebFeb 11, 2011 · Small ubiquitin-related modifier (SUMO)-1 promotes glycolysis in hypoxia Under conditions of hypoxia, most eukaryotic cells undergo a shift in metabolic strategy, which involves increased flux through the glycolytic pathway. Although this is critical for bioenergetic homeostasis, the underlying mechanisms have remained incompletely … WebSmall ubiquitin-related modifier (SUMO)-specific protease 2 (SENP2) is responsible for de-SUMOylation of target protein, with broad effects on cell growth, signal transduction, … north 3 condo

Modification of small ubiquitin‐related modifier 2 …

WebOct 12, 2015 · The mouse small ubiquitin-like modifier-2 (SUMO-2) inhibits interleukin-12 (IL-12) production in mature dendritic cells by blocking the translocation of the p65 subunit … WebSmall ubiquitin-related modifier (SUMO) 3The abbreviations used are: SUMO small ubiquitin-like modifier AFC 7-amino-4-trifluoromethyl coumarin DUB de-ubiquitinating enzyme SENP Sentrin-specific protease DTT dithiothreitol Ni-NTA nickel-nitrilotriacetic acid PIPES 1,4-piperazinediethanesulfonic acid MES 4-morpholineethanesulfonic acid CHES WebOct 1, 2024 · Sentrin/small ubiquitin-like modifier (SUMO) is protein modification pathway that regulates multiple biological processes, including cell division, DNA … how to renew link card

Small ubiquitin-related modifier (SUMO)-1 promotes glycolysis in ...

SUMO conjugation in plants SpringerLink

WebProtein target information for Small ubiquitin-related modifier 2 (tropical clawed frog). Find diseases associated with this biological target and compounds tested against it in bioassay experiments. WebSmall ubiquitin-like modifier 3 (SUMO3) is encoded by the gene mapped to human chromosome 21q22.3. The protein belongs to the ubiquitin-like protein family and is expressed mainly in cytoplasm. [ 1] [ 2] Immunogen human SUMO3 fusion protein Application Monoclonal Anti-Sumo-2/3 has been used in immunoblotting and … how to renew license sticker onlineWebSep 23, 2004 · Covalent attachment of small proteins to substrates can regulate protein activity in eukaryotes. SUMO, the s mall u biquitin-related mo difier, can be covalently linked to a broad spectrum of substrates. An understanding of … north 3pl beta

"WebFeb 22, 2005 · Importantly, Sp100 and PML are both covalently linked to small ubiquitin-related modifiers (SUMOs). Therefore, we investigated whether SUMO proteins are independent autoantigens in PBC and studied 99 PBC sera samples for reactivity against NDs, PML, and Sp100, as well as against SUMO-2 and SUMO-1 recombinant proteins. " - Small ubiquitin-related modifier 2

Small ubiquitin-related modifier 2

6613 - Gene ResultSUMO2 small ubiquitin like modifier 2 [ (human)]

WebUbiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Regulates the life cycle of promyelocytic leukemia nuclear bodies (PML-NBs). PolySUMO1P1/SUMO5 conjugation on 'Lys-160' of PML facilitates recruitment of PML-NB components, which enlarges PML-NB.

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WebNov 26, 2024 · Small ubiquitin-related modifiers (SUMOs) are a group of proteins known to greatly influence various cellular biological processes, 4 such as the cell cycle, signal … WebAug 10, 2008 · Small ubiquitin-related modifier (SUMO)-1, SUMO-2/3 and SUMOylation are involved with centromeric heterochromatin of chromosomes 9 and 1 and proteins of the synaptonemal complex during meiosis in men Petrice W. Brown, KeumSil Hwang, Peter N. Schlegel, Patricia L. Morris

WebOverview Product name Anti-Sumo 2 + Sumo 3 antibody See all Sumo 2 + Sumo 3 primary antibodies Description Rabbit polyclonal to Sumo 2 + Sumo 3 Host species Rabbit Specificity Recognises 2 bands representing Sumo 2 and Sumo 3 at 15 and 18kDa in Hela Nuclear extract by Western blotting. Tested applications In molecular biology, SUMO (Small Ubiquitin-like Modifier) proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their function. This process is called SUMOylation (sometimes written sumoylation). SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional re…

WebSUMOylation by generating mature small ubiquitin-related modifiers (SUMO) for protein conjugation (endopeptidase ... SUMO protease but functions on another small ubiquitin-re-latedproteinknownasNedd8(6,7).Thedefiningcharacteristic ... SUMO, small ubiquitin-like modifier; AFC, 7-amino-4-trifluoromethyl coumarin; DUB, de-ubiquitinating enzyme; WebSUMOylation is a reversible PTM that entails covalent ligation of small ubiquitin-related modifier (SUMO) groups at specific lysine residues. The SUMO family members (SUMO-1, -2, -3, and -4) belong to the group of ubiquitin-like protein-modifying enzymes. Similarly to ubiquitination, SUMOylation is a multistep process that involves an ...

WebAbstract. Posttranslational modification with small ubiquitin-related modifier (SUMO) proteins is now established as one of the key regulatory protein modifications in eukaryotic cells. Hundreds of proteins involved in processes such as chromatin organization, transcription, DNA repair, macromolecular assembly, protein homeostasis, trafficking ...

WebMay 1, 2009 · The present study aimed to produce and pathophysiologically evaluate the metallothionein (MT) fusion protein. A recombinant plasmid containing DNA segment coding the pET-glutathione transferase (GST)-small ubiquitin-related modifier (SUMO)-MT fusion protein was inserted into Escherichia coli for expression. The expression level of … north 3 starWebSmall ubiquitin-related modifier 2 is a protein that in humans is encoded by the SUMO2 gene. [5] Function [ edit] This gene encodes a protein that is a member of the SUMO … how to renew license tags onlineWebApr 13, 2024 · Tumor cells are known to produce high amounts of intracellular lipids, leading to increased levels of fatty acids, cholesterol and membrane phospholipids. Death domain-associated protein (DAXX) is a small ubiquitin-related modifier (SUMO)-binding protein that plays a role in transcription regulation by interacting with transcription factors such as … north 40 box scraperWebSUMOylation is a reversible PTM that entails covalent ligation of small ubiquitin-related modifier (SUMO) groups at specific lysine residues. The SUMO family members (SUMO-1, -2, -3, and -4) belong to the group of ubiquitin-like protein-modifying enzymes. Similarly to ubiquitination, SUMOylation is a multistep process that involves an ... north 40 cabinsWebSmall ubiquitin-related modifier 2/3 interacts with p65 and stabilizes it in the cytoplasm in HBV-associated hepatocellular carcinoma. Data show that substantial increases in the binding of small ubiquitin-like modifier 2 (SUMO-2) to active DNA regulatory elements in response to heat stress. how to renew llc in nevadaWebProtein target information for Small ubiquitin-related modifier 2 (tropical clawed frog). Find diseases associated with this biological target and compounds tested against it in … how to renew llc in mnWebMar 21, 2024 · SUMO2 (Small Ubiquitin Like Modifier 2) is a Protein Coding gene. Diseases associated with SUMO2 include Phlyctenulosis . Among its related pathways are Transport of the SLBP independent Mature mRNA and Homology Directed Repair . Gene Ontology (GO) annotations related to this gene include RNA binding and SUMO transferase activity . north 40 bale feeder